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Newberry, Robert  W
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Robert W Newberry

Assistant Professor
Department of Chemistry


Chemical Biology of Protein Misfolding

rnewberry@utexas.edu


Office Location
WEL

Postal Address
105 E 24TH ST
AUSTIN, TX 78712

Dr. Newberry completed his undergraduate education at The University of Texas at Austin in 2011, receiving a B.S. in Biochemistry from the Dean's Scholars Honors Program and a B.A. from the Plan II Honors Program. He also performed undergraduate research with Profs. Eric Anslyn and Lauren Webb. Dr. Newberry received his Ph.D. in chemical biology in 2016 from the University of Wisconsin-Madison under the direction of Prof. Ronald Raines. While at UW, Dr. Newberry was named an ACS Graduate Fellow and an HHMI Teaching Fellow. After receiving his Ph.D., Dr. Newberry undertook postdoctoral training in molecular biophysics under Prof. William DeGrado at the University of California, San Francisco. While at UCSF, Dr. Newberry received the NIH Pathway to Independence Award to support his return to UT Austin as an assistant professor in early 2022.

Proteins are the main machines of the cell, but they are prone to forming aberrant species in a process called protein misfolding. Not only are misfolded proteins incapable of performing their evolved functions, but they can actively interfere with the other activities a cell needs to perform to live. Protein misfolding is therefore implicated in many prevalent diseases, including Alzheimer's and Parkinson's, but unfortunately, we do not understand the nature of misfolded proteins or why they form, preventing effective disease interventions. The Newberry lab is working to solve these problems using approaches from chemistry and biology to understand protein misfolding in atomic detail.

Visit Dr. Newberry's Google Scholar page for a list of publications.