New next-generation genome analysis technology allows UT biochemists to target and enhance genomic research

A new “next-gen” genomic analysis system , SOLiD™, will allow UT researchers to quickly catalog large genomes and greatly increase the focus and pace of their research. The new technology is sponsored by the Texas Institute for Drug and Diagnostic Development, directed by chemistry professor Brent Iverson. This technology will be used by several genetics researchers at The University of Texas, including biochemistry professor Edward Marcotte. Dr. Marcotte studies protein-encoding genes and genetic networks, and expects his research to be greatly enhanced by the next-gen technology. He says, “This high-throughput sequencing system makes sequencing candidate genes from individuals suffering from disease dramatically easier. For example, we can now sequence 100 candidate genes from 100 patients for the same price as sequencing one gene from 100 patients using the conventional technology.”

The next-gen technology provides genomic analyses for several organisms, whereas such information used to only be available for well-researched organisms such as humans and fruit flies. This technology will allow University of Texas researchers to better understand the genetic causes of disease, develop better medical diagnostics, even understand animal behaviors such as aggression.

Learn more about the Marcotte Lab and The Texas Institute for Drug and Diagnostic Development.



Quote from Next Generation Gene Sequencing Technology Enables Advanced Genomic Research by Lee Clippard.