Emily Que's research group recently published a paper in the Journal of the American Chemical Society.
"Exploiting Copper Redox for 19F Magnetic Resonance-Based Detection of Cellular Hypoxia"
This paper describes a new MRI contrast agent platform that utilizes a Cu(II)/Cu(I) redox switch to selectively detect hypoxic environments in cells using fluorine MRI. Agents of this type have the potential to identify hypoxic tumors in vivo that may be resistant to chemotherapy treatments. This project was led by a 2nd year graduate student in the Que lab, Da (Ray) Xie.
