Graduate student Nancy Huynh of the Krische Group has been invited to participate in the Pfizer Organic Chemistry Symposium on Tuesday, November 10th. Nancy's research talk is titled, "Enantioselective Ruthenium-Catalyzed Benzocyclobutenone-Ketol Cycloaddition & Progress Towards the Total Synthesis of Arenimycin A" and is summarized below. The goal of this symposium is to champion diversity and inclusion.
Enantioselective Ruthenium-Catalyzed Benzocyclobutenone-Ketol Cycloaddition & Progress Towards the Total Synthesis of Arenimycin A
The emergence of antibiotic resistance is becoming a persistent problem. Still, antibiotics remain the gold standard of treatment for bacterial infections where constant search for novel chemical molecules remains a priority. The Krische group is utilizing methods of transfer-hydrogenative ruthenium-catalyzed transformations to access key motifs of type II polyketide natural products.
